Novel Tandem Three Consecutive Reactions: Aza-Wittig, Imine Condensation and Electrophilic Aromatic Substitution Strategy to Indolizine Synthesis
نویسندگان
چکیده
Reaction of ethyl (Z)-3-(heteroaryl/aryl)-2-((triphenyl-λ5-phosphaneylidene) amino) acrylates intermediates with 2,3-thiophenedicarboxaldehyde was used in novel Tandem three consecutive reactions: aza-Wittig, imine condensation and electrophilic heteroaromatic cyclization to obtain a series indolizines. A tentative mechanism this reaction is proposed.
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ژورنال
عنوان ژورنال: International Journal of Organic Chemistry
سال: 2021
ISSN: ['2161-4695', '2161-4687']
DOI: https://doi.org/10.4236/ijoc.2021.112006